A cura di Francesco Cirillo
Giant cell hepatitis with autoimmune haemolytic anaemia (GcH-aHa) is a rare and aggressive disease of infancy and may have fatal prognosis. it is presumed to be an autoimmune disease, but the mechanism of liver injury is unknown. immunosuppressive therapy may results in remission in mild forms while in severe forms, B cell depletion with rituximab can be an option. Liver transplantation may be a rescue treatment but relapse can occur in the graft.